The Microbiome in Rheumatic Diseases and Infection

Offers practicing clinicians intimate knowledge of the microbiome's role in rheumatic diseases and how this influences their daily practice Includes detailed basic science and immunology sections for clinicians to better understand the function of the microbiome Covers the role of infectious organisms in major rheumatic diseases including rheumatoid arthritis and vasculitis Experts from around the world offer a comprehensive and international perspective on the topic

Autorentext

Gaafar Ragab, MD is Professor of Internal Medicine at Cairo University and Fellow of the American College of Rheumatology. He was previously Head of the Clinical Immunology and Rheumatology unit at Cairo University.

T. Prescott Atkinson, MD, PhD is Professor/ Director of the Division of Pediatric Allergy, Asthma & Immunology at The Children's Hospital of Alabama. Matthew L. Stoll, MD, PhD is Associate Professor in the Division of Pediatric Rheumatology at the University of Alabama at Birmingham.

Zusammenfassung

Inhalt
Part I: The Human Microbiome.- Overview of the Human Microbiome.- Methods in Microbiome Studies: Collection.- Methods in Microbiome Studies: Informatics.- Part II: Immunogenetics of the Host Response to Infection.- Immunodeficiency and Autoimmunity.- Immunology of the Microbiome.- Lessons Learned from Animal Models on the Role of the Microbiome in Autoimmunity.- The Stroma in Chronic Inflammation.- Part III: Infections Agents.- Borrelia Burgdorferi.- Helicobacter Pylori.- Chlamydiae: Chlamydia Trachomatis and C. Pneumonia.- Mollicutes: Mycoplasma Pneumonia.- Role of Infection in Protection from Autoimmunity.- DNA Viruses.- RNA Viruses.- Human Immunodeficiency Virus Infection.- Enteroviruses.- Hepatitis A Virus.- Hepatitis C Virus.- Protozoal Infections.- Helminth Infections.- The Case for Fungi as Triggers for Autoimmunity.- Part IV: The Role of Infectious Agents in Rheumatic Diseases.- RA.- Spondylitis.- JIA.- Psoriasis & PSA.- Inflammatory Bowel Disease.- Reactive Arthritis.- Rheumatic Fever / Post-Streptococcal Glomerunlonephritis.- SLE.- APS.- Sjorgren's Syndrome.- Myositis.- Vasculitis Syndromes.- Cryoglobulinemia.- Behcet's.- Uveitis.- Sarcoidosis.- Autoinflammatory Syndromes.- Miscellaneous.- Part V: Practical Aspects.- Vaccinations in Rheumatology.- Management of Autoimmune Disorders During Infection / Immunodeficiency.- Individual Drugs in Rheumatology and the Risk of Infection.- The Microbiome: Towards Individualized Medicine