The Regulatory Genome

Gene regulatory networks are the most complex, extensive control systems found in nature. This book explains the control of animal development in terms of structure/function relations of inherited regulatory DNA sequence, and the emergent properties of the gene regulatory networks composed of these sequences.

Autorentext
Isabelle S. Peter is Assistant Research Professor and Eric H. Davidson is Norman Chandler Professor of Cell Biology in the Division of Biology and Biological Engineering at the California Institute of Technology, Pasadena, California. Over the last seven years they have co-authored a series of works on experimental, conceptual and computational analyses of developmental gene regulatory networks, including their evolutionary significance. The discussions and conceptual explorations occasioned by this collaboration produced the new synthetic views encompassed in this book, building on decades of earlier work summarized in the 2001 and 2006 Academic Press books by Eric H. Davidson.

Inhalt

CHAPTER 1
The "Regulatory Genome" for Animal Development

CHAPTER 2
cis-Regulatory Modules, and the Structure/Function Basis of Regulatory Logic

CHAPTER 3
Development as a Process of Regulatory State Specification

CHAPTER 4
Gene Regulatory Networks for Development: What They Are, How They Work, and What They Mean

CHAPTER 5
Gene Regulatory Networks: The Roots of Causality and Diversity in Animal Evolution