The Role of Polymorphism of Interleukin 10 and 12 in Hepatitis C

Chronic infection with hepatitis C virus (HCV) is a huge problem both globally and at the level of the individual patient. The natural outcome and response to treatment in hepatitis C virus (HCV) infection varies between individuals. It was aimed to detect single nucleotide polymorphisms (SNPs) of the IL-I0 promoter region at nucleotides -1082 &-592 and IL-12 promotor region at nucleotide -1188., also we measured Il-10 and IL12 protein level in the serum of chronic liver diseased patients under treatment with peg IFN- plus ribavirin and compare the results with non infected subjects.

Autorentext

Mohamed M. Hafez, Dozent für Biochemie und Molekularbiologie, Fakultät für Pharmazie, Ahram Canadian University (ACU), Ägypten. Mitglied des Redaktionsteams von The Journal of Nephrology and Therapeutics. Gutachterin für viele internationale Zeitschriften wie OMICS und BIO MED. Ich habe viele internationale Beiträge in vielen internationalen Fachzeitschriften veröffentlicht.