The Role of Rhes Protein in the Dopaminergic System of Rodents

Rhes is a new protein that is highly expressed in the
striatal system of rodents. In the present book, it
is described experimental work about the role of this
protein in behaviors mediated by the striatal
dopaminergic system. Some of the behavioral
paradigms described are stereotypy, anxiety and basal
levels of activity. The mutant mice model used is
the rhes ko mice. Female groups are included for all
the experiments. Very interesting gender differences
are found in anxiety and stereotypy. The present
work give evidence of the role of rhes protein in
dopamine receptor supersensitivity; this is relevant
for conditions like schizophrenia, Parkinson disease,
ADHD and others. This book represents one of the few
works that have been performed in the role of rhes
protein in behavioral neuroscience.

Autorentext

Dr. Gabriel C. Quintero G. was born in Panama City, Republic ofPanama. After finishing his B.A. in Psychology (U. of Panama) hewent to the United States for following Graduate Studies. He gota M.Sc. and Ph.D in the area of the neuroscience and behavior(Louisiana, U.S.A.).

Klappentext

Rhes is a new protein that is highly expressed in thestriatal system of rodents. In the present book, itis described experimental work about the role of thisprotein in behaviors mediated by the striataldopaminergic system. Some of the behavioralparadigms described are stereotypy, anxiety and basallevels of activity. The mutant mice model used isthe rhes ko mice. Female groups are included for allthe experiments. Very interesting gender differencesare found in anxiety and stereotypy. The presentwork give evidence of the role of rhes protein indopamine receptor supersensitivity; this is relevantfor conditions like schizophrenia, Parkinson disease,ADHD and others. This book represents one of the fewworks that have been performed in the role of rhesprotein in behavioral neuroscience.