The Vulnerable Brain and Environmental Risks

Contributors to this second volume discuss metal and toxicant toxicity, their environmental sources and methods of action, and their regulation by courts and agencies.

Inhalt
I. Metals.- 1 Methylmercury Neurotoxicity and Its Uptake Across the BloodBrain Barrier.- 2 The Neurotoxicity of Methylmercury in the Developing Nervous System.- 3 Intestinal Absorption of Aluminum: Relation to Neurotoxicity.- 4 Aluminum Ingestion: A Risk Factor for Alzheimer's Disease?.- 5 The Concept of Direct and Indirect Neurotoxicity and the Concept of Toxic Metal/Essential Element Interactions as a Common Biomechanism Underlying Metal Toxicity.- 6 Neurotoxic Metals and Neuronal Signalling Processes.- 7 Cognitive, Neural, and Behavioral Effects of Low-Level Lead Exposure.- 8 Lead Poisoning, Toxocariasis, and Pica: Links to Neurobehavioral Disorders.- 9 Nocardia: An Environmental Bacterium Possibly Associated with Neurodegenerative Diseases in Humans.- II. Toxicants.- 10 Neurotoxicity of Polychlorinated Biphenyls: The Role of Ortho-Substituted Congeners in Altering Neurochemical Function.- 11 Central Nervous System Plasticity and Pathology Induced by Exposure to Organophosphate Pesticides.- 12 Silver Impregnation of Organophosphorus-Induced Delayed Neuropathy in the Central Nervous System.- 13 Neuroreceptor and Behavioral Effects of DDT and Pyrethroids in Immature and Adult Mammals.- III. Selected Mechanisms of Action.- 14 Formation of Excess Reactive Oxygen Species within the Brain.- 15 Acute and Chronic Neurodegenerative Disorders Produced by Dietary Excitotoxins.- 16 Behavioral and Neuropathological Consequences of Chronic Exposure to Low Doses of the Dopaminergic Neurotoxin MPTP.- IV. Legal Issues.- 17 Courts, Agencies, and Social Risk Assessment.- Epilogue.