Toby Alderweireld

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High Quality Content by WIKIPEDIA articles! Tobramycin sulfate is an aminoglycoside antibiotic used to treat various types of bacterial infections, particularly Gram-negative infections.Tobramycin works by binding to a site on the bacterial 30S and 50S ribosome, preventing formation of the 70S complex. As a result, mRNA cannot be translated into protein and cell death ensues. Tobramycin is preferred over gentamicin for Pseudomonas aeruginosa pneumonia due to better lung penetration and bactericidal activity.Like all aminoglycosides, tobramycin does not pass the gastro-intestinal tract, so for systemic use it can only be given intravenously or intramuscularly. This formulation for injection is branded Nebcin. Patients with cystic fibrosis will often take an inhalational(nebulised) form (Tobi) for suppression of Pseudomonas aeruginosa infections. Tobramycin is also combined with dexamethasone as an ophthalmic solution (TobraDex).

Weitere Informationen

  • Allgemeine Informationen
    • Editor Lambert M. Surhone, Miriam T. Timpledon, Susan F. Marseken
    • Titel Toby Alderweireld
    • Format Fachbuch
    • EAN 9786131196904
    • Genre Medizin
    • Anzahl Seiten 124
    • Herausgeber Betascript Publishing
    • GTIN 09786131196904

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