Total Synthesis of Bioactive Natural Products

Total Synthesis of Bioactive Natural Products provides step-by-step guidelines for effectively synthesizing the most promising bioactive agents from a broad range of natural products. Beginning with a concise background that outlines the benefits and challenges faced in effective synthesis, the book goes on to provide individual outlines for approximately 100 of the most promising bioactive agents. Taking a logical, user-friendly approach, the systematic name, compound class, structure, natural source, pharmaceutical potential and synthetic routes for each structure are detailed, with clear illustrations throughout, making this book an essential and practical guide for anyone working with both synthesis and natural products.

Autorentext

Goutam Brahmachari is a Professor of Chemistry at Visva-Bharati University, India, with over 25 years of teaching and research experience. He specializes in synthetic organic chemistry, green chemistry, natural products chemistry, and medicinal chemistry of natural and synthetic molecules. Prof. Brahmachari has authored or edited 27 books with leading international publishers and serves as co-editor-in-chief of Current Green Chemistry, as well as being the founding series editor of Elsevier's Natural Product Drug Discovery series. An elected Fellow of the Royal Society of Chemistry, he has received prestigious awards such as the CRSI Bronze Medal (2021) and the INSA Teachers Award (2019).

Inhalt

Aeruginosins 298-A and B
Ageladine A
(+)-Ainsliadimer A-(+)
(?)-Aiphanol
(+)-Amphidinolide T1
Ancistroealaine A and Ancistrotanzanine B
(?)-Andrographolide
Anolignan A
Anolignan B
Antrocamphin A
Arenamide A
Atroviridin
Bauhinoxepin J
Beta-Lapachone
Bombykol
Bulbophylol-B
Caminoside A
(+)-Chaetocin
Ciliatamides A and B
Cylindol A
Daedalin A
6-Deoxypladienolide D
7-Desmethoxyfusarentin and its methyl ether
Etnangien
(+)-Gliocladin B
(+)-Harziphilone
Hibarimicinone
(±)-3-Hydroxy-beta-ionone
Hyperforin
Integric acid
Jineol
Karalicin
(?)-Kunstleramide
(±)-Limonin
Linderaspirone A and Bi-linderone
Lucidone
(±)-Marinopyrrole A
Martefragin A
(?)-Melotenine A
Microcin SF608
Nemorosone
Nicotlactone A
(?)-6-O-Desmethylantofine
Oleocanthal
(+)-3-Oxo-?-ionol
Paecilomycin B
Paecilomycine A?
Pochonin A
Rhinacanthin A
Rubriflordilactone A
(+)-Sattazolin
Somocystinamide A
(?)-Stagonolide A
(±)-Steenkrotin A
Thiaplakortone A and its semi-synthetic derivatives
Vinigrol
Withaferin A
Withanolide A
(+)-Xylarenal A
Xyolide