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Transrepression
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Geliefert zwischen Do., 19.02.2026 und Fr., 20.02.2026
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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. In the field of molecular biology, transrepression is a process whereby one protein represses (i.e., inhibits) the activity of a second protein through a protein-protein interaction. Since this repression occurs between two different protein molecules (intermolecular), it is refered to as a trans-acting process. The protein that is repressed is usually a transcription factor whose function is to up-regulate (i.e., increase) the rate of gene transcription. Hence the net result of transrepression is down regulation of gene transcription. The phenomena of transrepression was first observed in the ability of the glucocorticoid receptor to inhibit the transcriptional promoting activity of the AP-1 and NF- B transcription factors. In addition to transactivation, transrepression is an important pathway for the anti-inflammatory effects of glucocorticoids. Since then, other nuclear receptors such as LXR and PPAR have been demonstrated to also have the ability to transrepress the activity of other proteins.
Weitere Informationen
- Allgemeine Informationen
- GTIN 09786130972240
- Editor Lambert M. Surhone, Miriam T. Timpledon, Susan F. Marseken
- Größe H220mm x B220mm
- EAN 9786130972240
- Format Fachbuch
- Titel Transrepression
- Herausgeber Betascript Publishing
- Anzahl Seiten 112
- Genre Biologie
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