Triazole, Indol-Pyrimidine and Trione

Heterocyclic compound where benzene is fused with pyrrole ring. It was first identified by Baeyer in 1866 while doing research on the structure of natural dye indigo. Indole pharmacophore is a ubiquitous constituent of many natural products which includes plant hormones (indole-3-acetic acid), some animal hormones such as melatonin and serotonin and many alkaloids that includes vinblastine, vincristine, vindesine, vinorelbine, ajmaline and physostigmine. Similarly it is main component of several synthetic drugs such as indomethacin, fluvastatin, zafirlukast and ondansetron.

Autorentext

Dr. B. Ashok Kumar working as an Assistant Professor in the Department of Chemistry, GURU NANAK INSTITUTIONS TECHNICALCAMPUS (AUTONOMOUS) School of Engineering and Technology, Ibrahimpatnam, R R. District, TS 501506.,has about 15 years of teaching experience. He received Ph.D. degree in Organic Chemistry from KL Deemed to be University, AP state.