Tuberculosis

The gratifYing response to the first edition of Tuberculosis has prompted this revision. There are many important changes incorporated into this edition, including the dramatic effect of AIDS on the incidence and clinical mani festations of mycobacterial infection, new developments in epidemiology and bacteriology, and thoroughly updated therapeutic recommendations and principles of prophylaxis. The chapters that deal with clinical manifestations of tuberculosis have also been updated and include important and clinically applicable information on manifestations of tuberculosis in both the normal and immunocomprom ised host. As with the first edition, it is hoped that this text will continue to represent a definitive resource for both the basic scientist and the clinician who deal with the prevention and treatment of mycobacterial infection. II Preface to the First Edition We have just witnessed the lOOth anniversary of Koch's discovery of the tubercle bacillus. This event did not end the centuries-long saga of tuber culosis, however; it was but one major step in the ongoing struggle to un derstand and combat this disease. Tuberculosis is very much with us today, and its clinical manifestations and principles of treatment must be understood by both the primary care physician and the specialist. This monograph covers all aspects of tuberculosis in a single volume. It is divided into three parts, covering, respectively, general considerations, clin ical manifestations, and atypical mycobacterial infection.

Inhalt

1. Epidemiology and Host Factors.- 2. Pathogenesis and Immunology: Basic Aspects.- 3. Pathophysiology and Immunology: Clinical Aspects.- 4. Bacteriology and Bacteriologic Diagnosis of Tuberculosis.- 5. Tuberculin Skin Testing.- 6. Chemotherapy of Tuberculosis.- 7. Prophylaxis.- 8. Pulmonary Tuberculosis.- 9. Upper Respiratory Tract Tuberculosis.- 10. Otologic Tuberculosis.- 11. Ocular Tuberculosis.- 12. Central Nervous System Tuberculosis.- 13. Tuberculous Lymphadenitis.- 14. Genitourinary Tuberculosis.- 15. Bone and Joint Tuberculosis.- 16. Cardiovascular Tuberculosis.- 17. Mycobacterial Enteritis.- 18. Tuberculous Peritonitis.- 19. Tuberculosis of the Liver and Biliary Tract.- 20. Cutaneous Tuberculosis.- 21. Miliary Tuberculosis.- 22. Endocrine and Metabolic Aspects of Tuberculosis.- 23. Hematologic Changes in Tuberculosis.- 24. Human Immunodeficiency Virus and Mycobacterial Infections.- 25. Perinatal Tuberculosis.- 26. Clinical Syndromes and Diagnosis of Nontuberculous (Atypical) Mycobacterial Infection.- 27. Treatment of Diseases Caused by Nontuberculous Mycobacteria.