Tumor Markers in Head and Neck Oncology

Malignant neoplasms are a significant cause of fear, morbidity, and mortality worldwide. Oral cancer ranks as the sixth most common cause of cancer-related deaths globally and accounts for approximately 30 to 40% of all cancers in India. Despite recent advances in tumor surgery and multimodal treatment regimens, the prognosis for oral cancer remains relatively poor. The oral mucosa, as the initial part of the digestive tract, is exposed to various toxins. Prolonged exposure can lead to changes that contribute to potentially malignant diseases or cancers. The future holds tremendous promise for the field of tumor markers. Molecular analysis, rather than morphological assessment, will categorize human diseases due to advancements in genomic and proteomic technology. This will involve combining genomic and proteomic analysis, along with techniques like laser capture micro-dissection for tissue and cell collection. Early disease diagnosis is achievable using unique gene or protein profiles comprising multiple biomarkers.

Autorentext

• Dr. Shamli Jaydeep Sadawarte, MDS em Medicina Oral e Radiologia.Publicou mais de 10 artigos em várias revistas nacionais e internacionais. Apresentou trabalhos e posters em várias conferências.- Dr. Chaitanya Mahajan, MBBS, MS (Cirurgia Geral).- Dr. Saurabh Mahajan, BDS.