Tumor Microenvironment

Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research in the field. A variety of topics are covered, including metabolism in the tumor microenvironment, stellate cells and endothelial progenitors in the tumor microenvironment, as well as the effects of HIV, viral hepatitis, and inflammation in the tumor microenvironment, and more.

Taken alongside its companion volumes, Tumor Microenvironment: State of the Science updates us on what we know about various aspects of the tumor microenvironment, as well as future directions. This book is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.

Provides a comprehensive overview of the various components that make up the tumor microenvironment Explores the effects different viruses, such as hepatitis virus and HIV, have on the tumor microenvironment Discusses the ways in which the cellular composition of the microenvironment promote and/or limit tumor progression

Autorentext
Alexander Birbrair received his Bachelor's Biomedical degree from Santa Cruz State University in Brazil. He moved to North Carolina, where he finished his PhD in Neuroscience under the mentorship of Osvaldo Delbono. Then, he joined as a posdoc in Stem Cell Biology at Paul Frenette's laboratory at Albert Einstein School of Medicine. In 2016, he was appointed faculty at Federal University of Minas Gerais in Brazil, where he started his own lab. His laboratory is interested in understanding how the cellular components of different tissues function and control disease progression. His group explores the roles of specific cell populations in the tissue microenvironment by using state-of-the-art techniques. His research is funded by the Serrapilheira Institute, CNPq, CAPES, and FAPEMIG. In 2018, Alexander was elected affiliate member of the Brazilian Academy of Sciences (ABC), and, in 2019, he was elected member of the Global Young Academy (GYA).

Inhalt
Metabolism in the tumor microenvironment.- Neutrophil Elastase and Neutrophil Extracellular Traps in the Tumor Microenvironment.- Viral hepatitis, inflammation, and tumour microenvironment.- Effects of HIV on the tumor microenvironment.- GLI2-mediated inflammation in the tumor microenvironment.- Stellate Cells in the Tumor Microenvironment.- Endothelial Progenitors in the Tumor microenvironment.- Chimeric antigen receptors for the tumour microenvironment.- Toll-Like Receptors (TLRs) in the Tumor Microenvironment (TME): A dragon-Like Weapon in a Non-Fantasy Game of Thrones.- Multiple dynamics in tumor microenvironment under radiotherapy.- Index. <p