UBE1C

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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. NEDD8-activating enzyme E1 catalytic subunit is a protein that in humans is encoded by the UBA3 gene. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis.

Weitere Informationen

  • Allgemeine Informationen
    • Editor Lambert M. Surhone, Mariam T. Tennoe, Susan F. Henssonow
    • Titel UBE1C
    • Format Fachbuch
    • EAN 9786131229336
    • Größe H220mm x B220mm
    • Genre Medizin
    • Anzahl Seiten 132
    • Herausgeber Betascript Publishing
    • GTIN 09786131229336

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