UQCRB
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High Quality Content by WIKIPEDIA articles! Ubiquinol-cytochrome c reductase binding protein, also known as UQCRB, is a protein which in humans is encoded by the UQCRB gene. The ubiquinone-binding protein is a nucleus-encoded component of ubiquinol-cytochrome c oxidoreductase (Complex III; EC 1.10.2.2) in the mitochondrial respiratory chain and plays an important role in electron transfer as a complex of ubiquinone and QP-C. Complex III consists of 10 nuclear-encoded subunits and 1 mitochondrial-encoded subunit. The bovine gene product (subunit 6) was sequenced under the name "ubiquinone-binding protein", however there is little or no evidence for a role in ubiquinone binding. Subunit 7 was identified as a Q-binding protein by photo-labeling with a ubiquinone analog (subsequent structures show it to be exposed to the lipid phase but not involved in either Q-binding site). Subunits 6 and 7 reverse position on going from Laemli gels to Weber&Osborne gels, and one might suspect the name "Q-binding protein" arose from confusion with subunit 7.
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GarantieWeitere Informationen
- Allgemeine Informationen
- Editor Lambert M. Surhone, Mariam T. Tennoe, Susan F. Henssonow
- Titel UQCRB
- EAN 9786131105777
- Größe H220mm x B220mm
- Genre Medizin
- Anzahl Seiten 80
- Herausgeber Betascript Publishing
- GTIN 09786131105777
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