Viral Replication Enzymes and their Inhibitors Part A: Volume 49

Viral Replication Enzymes and their Inhibitors Part A, Volume 49, the latest release in the Enzymes series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of related topics.

Autorentext
Craig E. Cameron is at UNC School of Medicine, NC, USA Jamie J. Arnold is at UNC School of Medicine, Chapel Hill, NC, USA

Inhalt
Preface * Craig E. Cameron, Jamie J. Arnold and Laurie S. Kaguni

• 1. CoV-er all the bases: Structural perspectives of SARS-CoV-2 RNA synthesis
  * Brandon Malone, Seth A. Darst and Elizabeth A. Campbell
• 2. Mechanisms of inhibition of viral RNA replication by nucleotide analogs
  * Kenneth A. Johnson and Tyler Dangerfield
• 3. HCV RdRp, sofosbuvir and beyond
  * Joy Y. Feng and Adrian S. Ray
• 4. Understanding viral replication and transcription using single-molecule techniques
  * Emmanuelle Pitre and Aartjan J.W. te Velthuis
• 5. In vitro single-molecule manipulation studies of viral DNA replication
  * Rebeca Bocanegra, Ismael Plaza-G.A. and Borja Ibarra
• 6. Allosteric and dynamic control of RNA-dependent RNA polymerase function and fidelity
  * Dennis S. Winston and David D. Boehr
• 7. Single-cell analysis for the study of viral inhibitors
  * Mohamad S. Sotoudegan, Jamie J. Arnold and Craig E. Cameron
• 8. Structural basis of viral RNA-dependent RNA polymerase nucleotide addition cycle in picornaviruses
  * Peng Gong
• 9. Picornaviral 2C proteins: A unique ATPase family critical in virus replication
  * Pu Chen, Zhijian Li and Sheng Cui
• 10. Flavivirus enzymes and their inhibitors * Ekaterina Knyazhanskaya, Marc C. Morais and Kyung H. Choi
• 11. Watching the bacterial RNA polymerase transcription reaction by time-dependent soak-trigger-freeze X-Ray crystallography * Yeonoh Shin and Katsuhiko S. Murakami
• 12. Inhibition of viral RNA-dependent RNA polymerases with clinically relevant nucleotide analogs Kieran Maheden, Brendan Todd, Calvin J. Gordon, Egor P. Tchesnokov and Matthias Götte